Feasibility of predicting allele specific expression from DNA sequencing using machine learning
نویسندگان
چکیده
منابع مشابه
Allele-specific copy number profiling by next-generation DNA sequencing
The progression and clonal development of tumors often involve amplifications and deletions of genomic DNA. Estimation of allele-specific copy number, which quantifies the number of copies of each allele at each variant loci rather than the total number of chromosome copies, is an important step in the characterization of tumor genomes and the inference of their clonal history. We describe a ne...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2021
ISSN: 2045-2322
DOI: 10.1038/s41598-021-89904-y